Renee Wegryzn Tapped to Head ARPA-H

As the new agency's director, the DARPA veteran will spearhead a high-risk, high-reward approach to biomedical research.…

Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains

Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.…

The Noncoding Regulators of the Brain

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.…

William Harvey Revolutionizes Understanding of Circulation

A puzzle for millennia, the movement of blood through the body was solved by an English physician in the 17th century, paving the way for modern medical technologies.…

Infographic: Vangl2 in Muscles Keeps Neuromuscular Junctions Organized

Genetic knockout experiments reveal a role for the protein in forming and maintaining synapses between motor neurons and muscle fibers in mice.…

A Novel Player at the Neuromuscular Junction

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between those muscles and motor neurons, a study concludes.…

Human Gut Bacteria Show Up in Urban Wildlife

The gut microbiomes of city-dwelling animals, including coyotes, lizards, and birds, show similarities to those found in humans who also live in urban environments.…

How to Fix Science's Code Problem

Despite increasingly strict journal policies requiring the release of computational code files along with research papers, many scientists remain reluctant to share—underscoring the need for better solutions.…

Caught on Camera

See some of the coolest images recently featured by The Scientist…

Infographic: Noncoding RNA in the Brain

Neurologically important noncoding RNAs come in many shapes and sizes.…

Building Better Biosafety Labs

Considerations for setting up and maintaining biosafety labs.…

Vitamin D Likely Doesn’t Prevent COVID-19, Studies Find

The results from two large clinical trials refute the idea that supplements of the vitamin bolster immune defenses against SARS-CoV-2.…

Mutation Linked to Difference Between Human and Neanderthal Brains

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a…

Mouse Brains Appear to Eavesdrop on Their Fat

For the first time, a team visualizes sensory nerves projecting into adipose tissue in mice and finds these neuronal cells may counteract the local effects of the sympathetic nervous system.…

Independent FDA Advisory Panel Recommends Approving ALS Drug

The group’s 7-2 ruling in favor of the therapeutic represents a shift from previous deliberations, in which data on its effectiveness was deemed insufficient.…

Science Snapshot: Pin the Domestication On The Donkey

A genomic analysis reveals that humans domesticated donkeys more than 7,000 years ago.…

31,000-Year-Old Skeleton Reveals Oldest Known Surgery

A Stone Age individual’s left leg healed after being amputated just above the foot, allowing them to survive for six to nine years after the procedure was performed, researchers say.…

Finding The Cause of Mammoth Extinction

Environmental DNA and climate change data suggest that vegetation scarcity led to the mass extinction of herbivore species, including Arctic mammoths.…

Scientists Consider How Overturning Roe Might Affect Research

Researchers who work with materials such as fetal tissue and human embryonic stem cells are facing new restrictions, the latest in a long line of regulations, that could impede important…

Best Practices for Designing and Executing Successful Flow Cytometry Experiments

A roadmap to navigating flow cytometry…

A New Culprit in Air Pollution: Reactions Triggered by Human Skin

Oil on human skin reacts with ozone to produce highly reactive radicals that can generate toxic airborne chemicals in indoor spaces.…

Secret to Reproductive Ants' Longevity Revealed

Researchers say they've figured out how some reproductive ants live up to 30 years--far longer than workers.…

Corals Upend Longstanding Idea About Genetic Inheritance

Most animals can’t pass on mutations that arise spontaneously throughout their lives—but Elkhorn corals can.…

Dog Ancestry Provides Clues to Ancient Human Activities

Researchers combined evidence found in dog genomes with physical materials recovered from archeological sites to discover factors behind major societal changes.…

RNA Pioneer Christine Guthrie Dies at 77

Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.…

September 2022 Interactive Crossword Puzzle

Infographic: The Sequencing and Assembly of the Human Genome

With ever-advancing genetic technologies, researchers continue to document the genetic code of the human species.…

Large Scientific Collaborations Aim to Complete Human Genome

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete…